Years ago our doctor had a student doctor with her and asked her to give her thoughts on my wife’s issue. She added the wise words, “Don’t put emphasis of the fact that she is Asian, she has lived in America for many years.” A case for environmental concerns in addition to genetics.
Another example is my daughter. Doctors thought she was a hypochondriac for years when she complained of stomach pain. Finally, one doctor chatted her up enough to learn that she had lived overseas in Southeast Asia. Parasites! At the time American doctors limited their thoughts on environmental influence to the current local environment.
Where are you and where have you been matters along with genetics. Good article on limitations of generic influence.